| Accession | TIGR02865 |
| Name | spore_II_E |
| Function | stage II sporulation protein E |
| Gene Symbol | spoIIE |
| Trusted Cutoff | 490.80 |
| Domain Trusted Cutoff | 490.80 |
| Noise Cutoff | 201.15 |
| Domain Noise Cutoff | 201.15 |
| Isology Type | equivalog |
| EC Number | 3.1.3.16 |
| HMM Length | 764 |
| Mainrole Category | Cellular processes |
| Subrole Category | Sporulation and germination |
| Gene Ontology Term | GO:0004722: protein serine/threonine phosphatase activity molecular_function |
| | GO:0016020: membrane cellular_component |
| | GO:0030436: asexual sporulation biological_process |
| Author | Haft DH |
| Entry Date | Mar 6 2006 8:43AM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Stage II sporulation protein E (SpoIIE) is a multiple membrane spanning protein with two separable functions. It plays a role in the switch to polar cell division during sporulation. By means of it protein phosphatase activity, located in the C-terminal region, it activates sigma-F. All proteins that score above the trusted cutoff to this model are found in endospore-forming Gram-positive bacteria. Surprisingly, a sequence from the Cyanobacterium-like (and presumably non-spore-forming) photosynthesizer Heliobacillus mobilis is homologous, and scores between the trusted and noise cutoffs. |
| References | RN [1]
RM 15866939
RT Genetic dissection of the sporulation protein SpoIIE and its role in asymmetric division in Bacillus subtilis.
RA Carniol K, Ben-Yehuda S, King N, Losick R.
RL J Bacteriol. 2005 May;187(10):3511-20. |
| Genome Property | GenProp0610: endospore formation marker gene set (HMM) |
