HMM Summary Page: TIGR02897

Functioncytochrome aa3 quinol oxidase, subunit III
Gene SymbolqoxC
Trusted Cutoff239.90
Domain Trusted Cutoff239.90
Noise Cutoff228.60
Domain Noise Cutoff228.60
Isology Typeequivalog
EC Number1.10.3.-
HMM Length190
Mainrole CategoryEnergy metabolism
Subrole CategoryElectron transport
Gene Ontology TermGO:0015002: heme-copper terminal oxidase activity molecular_function
GO:0015078: hydrogen ion transmembrane transporter activity molecular_function
GO:0015990: electron transport coupled proton transport biological_process
GO:0016682: oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor molecular_function
GO:0055114: oxidation-reduction process biological_process
AuthorSelengut J
Entry DateMar 16 2006 2:55PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis family (QoxC) encodes subunit III of the aa3-type quinone oxidase, one of several bacterial terminal oxidases [1]. This complex couples oxidation of reduced quinones with the reduction of molecular oxygen to water and the pumping of protons to form a proton gradient utilized for ATP production. aa3-type oxidases contain two heme a cofactors as well as copper atoms in the active site.
ReferencesRN [1] RM PMID: 7575098 RT Properties of the menaquinol oxidase (Qox) and of qox deletion mutants of Bacillus subtilis. RA Lemma E, Simon J, Schagger H, Kroger A. RL Arch Microbiol. 1995 Jun;163(6):432-8.
Genome PropertyGenProp0620: cytochrome (quinone) oxidase, aa3 type, QoxABCD (HMM)
GenProp0614: cytochrome c oxidase, mitochondrial, caa3-type (SUBFAM-EX)