| Accession | TIGR02899 |
| Name | spore_safA |
| Function | spore coat assembly protein SafA |
| Gene Symbol | safA |
| Trusted Cutoff | 67.85 |
| Domain Trusted Cutoff | 67.85 |
| Noise Cutoff | 58.90 |
| Domain Noise Cutoff | 58.90 |
| Isology Type | subfamily_domain |
| HMM Length | 44 |
| Mainrole Category | Cellular processes |
| Subrole Category | Sporulation and germination |
| Gene Ontology Term | GO:0003674: molecular_function molecular_function |
| | GO:0030436: asexual sporulation biological_process |
| Author | Haft DH |
| Entry Date | Mar 17 2006 1:02PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | SafA (YrbB) (SafA) of Bacillus subtilis is a protein found at the interface of the spore cortex and spore coat, and is dependent on SpoVID for its localization. This model is based on the N-terminal LysM (lysin motif) domain (see PFAM model PF01476) of SafA and, from several other spore-forming species, the protein with the most similar N-terminal region. However, this set of proteins differs greatly in C-terminal of the LysM domaim; blocks of 12-residue and 13-residue repeats are found in the Bacillus cereus group, tandem LysM domains in Thermoanaerobacter tengcongensis MB4, etc.
in which one of which is found in most examples of endospore-forming bacteria. Because lysin motifs are repeated in many proteins, this model is built as a single-hit (-g option, hmms style) model. |
| References | RN [1]
RM PMID: 11325931
RT SpoVID guides SafA to the spore coat in Bacillus subtilis.
RA Ozin AJ, Samford CS, Henriques AO, Moran CP Jr
RL J Bacteriol. 2001 May;183(10):3041-9.
RN [2]
RM PMID: 12480901
RT Proteomics characterization of novel spore proteins of Bacillus subtilis.
RA Kuwana R, Kasahara Y, Fujibayashi M, Takamatsu H, Ogasawara N, Watabe K
RL Microbiology. 2002 Dec;148(Pt 12):3971-82.
DR PFAM; PF01476; LysM domain |
| Genome Property | GenProp0610: endospore formation marker gene set (HMM) |
