HMM Summary Page: TIGR02965

Functionxanthine dehydrogenase, molybdopterin binding subunit
Gene SymbolxdhB
Trusted Cutoff849.50
Domain Trusted Cutoff849.50
Noise Cutoff691.00
Domain Noise Cutoff691.00
Isology Typeequivalog
EC Number1.17.1.4
HMM Length758
Mainrole CategoryPurines, pyrimidines, nucleosides, and nucleotides
Subrole CategoryOther
Gene Ontology TermGO:0004854: xanthine dehydrogenase activity molecular_function
GO:0009115: xanthine catabolic process biological_process
GO:0043546: molybdopterin cofactor binding molecular_function
AuthorHaft DH
Entry DateJun 8 2006 1:41PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of the protein family are the molybdopterin-containing large subunit (or, in, eukaryotes, the molybdopterin-binding domain) of xanthine dehydrogenase, and enzyme that reduces the purine pool by catabolizing xanthine to urate. This model is based primarily on bacterial sequences; it does not manage to include all eukaryotic xanthine dehydrogenases and thereby discriminate them from the closely related enzyme aldehyde dehydrogenase.
Genome PropertyGenProp0640: xanthine dehydrogenase (HMM)