HMM Summary Page: TIGR02977

Functionphage shock protein A
Gene SymbolpspA
Trusted Cutoff242.95
Domain Trusted Cutoff242.95
Noise Cutoff170.25
Domain Noise Cutoff170.25
Isology Typeequivalog
HMM Length219
Mainrole CategoryCellular processes
Subrole CategoryAdaptations to atypical conditions
AuthorHaft DH
Entry DateJun 23 2006 8:53AM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this family are the phage shock protein PspA, from the phage shock operon. This is a narrower family than the set of PspA and its homologs, sometimes several in a genome, as described by PFAM model PF04012. PspA appears to maintain the protonmotive force under stress conditions that include overexpression of certain phage secretins, heat shock, ethanol, and protein export defects.
ReferencesDR PFAM; PF04012; PspA/IM30 family RN [1] RM PMID: 8598199 RT Involvement of stress protein PspA (phage shock protein A) of Escherichia coli in maintenance of the protonmotive force under stress conditions. RA Kleerebezem M, Crielaard W, Tommassen J RL EMBO J. 1996 Jan 2;15(1):162-71.
Genome PropertyGenProp0648: phage shock protein regulon (HMM)