HMM Summary Page: TIGR02978

Functionphage shock protein C
Gene SymbolpspC
Trusted Cutoff104.00
Domain Trusted Cutoff104.00
Noise Cutoff71.35
Domain Noise Cutoff71.35
Isology Typeequivalog
HMM Length121
Mainrole CategoryCellular processes
Subrole CategoryAdaptations to atypical conditions
AuthorHaft DH
Entry DateJun 23 2006 10:33AM
Last ModifiedFeb 14 2011 3:27PM
CommentAll members of this protein family are the phage shock protein PspC. These proteins contain a PspC domain, as do other members of the larger family of proteins described by Pfam model PF04024. The phage shock regulon is restricted to the Proteobacteria and somewhat sparsely distributed there. It is expressed, under positive control of a sigma-54-dependent transcription factor, PspF, which binds and is modulated by PspA. Stresses that induce the psp regulon include phage secretin overexpression, ethanol, heat shock, and protein export defects.
ReferencesDR PFAM; PF04024; PspC domain RN [1] RM PMID: 16468999 RT PspB and PspC of Yersinia enterocolitica are dual function proteins: regulators and effectors of the phage-shock-protein response. RA Maxson ME, Darwin AJ RL Mol Microbiol. 2006 Mar;59(5):1610-23.
Genome PropertyGenProp0648: phage shock protein regulon (HMM)