HMM Summary Page: TIGR03005

Functionectoine/hydroxyectoine ABC transporter, ATP-binding protein EhuA
Gene SymbolehuA
Trusted Cutoff345.40
Domain Trusted Cutoff345.40
Noise Cutoff345.20
Domain Noise Cutoff345.20
Isology Typeequivalog
HMM Length252
Gene Ontology TermGO:0005524: ATP binding molecular_function
GO:0009898: internal side of plasma membrane cellular_component
GO:0033286: ectoine-transporting ATPase activity molecular_function
GO:0033288: hydroxyectoine-transporting ATPase activity molecular_function
GO:0033308: hydroxyectoine transport biological_process
GO:0051470: ectoine transport biological_process
AuthorHaft DH
Entry DateJul 14 2006 11:58AM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this family are the ATP-binding protein of a conserved four gene ABC transporter operon found next to ectoine unilization operons and ectoine biosynthesis operons. Ectoine is a compatible solute that protects enzymes from high osmolarity. It is released by some species in response to hypoosmotic shock, and it is taken up by a number of bacteria as a compatible solute or for consumption. This family shows strong sequence similiarity to a number of amino acid ABC transporter ATP-binding proteins.
ReferencesRM PMID: 15687193 RT Ectoine-induced proteins in Sinorhizobium meliloti include an Ectoine ABC-type transporter involved in osmoprotection and ectoine catabolism. RA Jebbar M, Sohn-Bosser L, Bremer E, Bernard T, Blanco C RL J Bacteriol. 2005 Feb;187(4):1293-304.
Genome PropertyGenProp0651: ectoine ABC transporter EhuABCD (HMM)