HMM Summary Page: TIGR03031

FunctionCRISPR-associated protein Cas9/Csx12, subtype II-B/NMENI
Gene Symbolcas9
Trusted Cutoff399.40
Domain Trusted Cutoff399.40
Noise Cutoff399.00
Domain Noise Cutoff399.00
Isology Typehypoth_equivalog
HMM Length802
Mainrole CategoryMobile and extrachromosomal element functions
Subrole CategoryOther
Gene Ontology TermGO:0003674: molecular_function molecular_function
GO:0043571: maintenance of CRISPR repeat elements biological_process
AuthorHaft DH
Entry DateAug 3 2006 1:32PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this family of CRISPR-associated (cas) protein are found, so far, in CRISPR/cas loci in Wolinella succinogenes DSM 1740, Legionella pneumophila str. Paris, and Francisella tularensis, where the last probably is an example of a degenerate CRISPR locus, having neither repeats nor a functional Cas1. The characteristic repeat length is 37 base pairs and period is about 72. One region of this large protein shows sequence similarity to PFAM model PF01844, HNH endonuclease.
Genome PropertyGenProp0021: CRISPR region (HMM)