| Accession | TIGR03037 |
| Name | anthran_nbaC |
| Function | 3-hydroxyanthranilate 3,4-dioxygenase |
| Gene Symbol | nbaC |
| Trusted Cutoff | 145.95 |
| Domain Trusted Cutoff | 145.95 |
| Noise Cutoff | 57.60 |
| Domain Noise Cutoff | 57.60 |
| Isology Type | equivalog |
| EC Number | 1.13.11.6 |
| HMM Length | 159 |
| Author | Haft DH |
| Entry Date | Aug 8 2006 1:57PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Members of this protein family, from both bacteria and eukaryotes, are the enzyme 3-hydroxyanthranilate 3,4-dioxygenase. This enzyme acts on the tryptophan metabolite 3-hydroxyanthranilate and produces 2-amino-3-carboxymuconate semialdehyde, which can rearrange spontaneously to quinolinic acid and feed into nicotinamide biosynthesis, or undergo further enzymatic degradation. |
| References | RN [1]
RM PMID: 12620844
RT Prokaryotic homologs of the eukaryotic 3-hydroxyanthranilate 3,4-dioxygenase and 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase in the 2-nitrobenzoate degradation pathway of Pseudomonas fluorescens strain KU-7.
RA Muraki T, Taki M, Hasegawa Y, Iwaki H, Lau PC
RL Appl Environ Microbiol. 2003 Mar;69(3):1564-72.
DR HAMAP; MF_00825; 15 of 15 |
