HMM Summary Page: TIGR03074

AccessionTIGR03074
NamePQQ_membr_DH
Functionmembrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family
Trusted Cutoff832.65
Domain Trusted Cutoff832.65
Noise Cutoff552.25
Domain Noise Cutoff552.25
Isology Typesubfamily
EC Number1.1.-.-
HMM Length783
Gene Ontology TermGO:0016491: oxidoreductase activity molecular_function
GO:0016491: oxidoreductase activity molecular_function
GO:0016491: oxidoreductase activity molecular_function
GO:0050662: coenzyme binding molecular_function
GO:0050662: coenzyme binding molecular_function
GO:0050662: coenzyme binding molecular_function
AuthorHaft DH
Entry DateSep 20 2006 10:38AM
Last ModifiedFeb 14 2011 3:27PM
CommentThis protein family has a phylogenetic distribution very similar to that coenzyme PQQ biosynthesis enzymes, as shown by partial phylogenetic profiling. Members of this family have several predicted transmembrane helices in the N-terminal region, and include the quinoprotein glucose dehydrogenase (EC 1.1.5.2) of Escherichia coli and the quinate/shikimate dehydrogenase of Acinetobacter sp. ADP1 (EC 1.1.99.25). Sequences closely related except for the absense of the N-terminal hydrophobic region, scoring in the gray zone between the trusted and noise cutoffs, include PQQ-dependent glycerol (EC 1.1.99.22) and and other polyol (sugar alcohol) dehydrogenases.
ReferencesDR PFAM; PF01011; PQQ enzyme repeat
Genome PropertyGenProp0170: coenzyme PQQ biosynthesis (HMM)
GenProp0170: coenzyme PQQ biosynthesis (HMM)
GenProp0170: coenzyme PQQ biosynthesis (HMM)