| Accession | TIGR03074 |
| Name | PQQ_membr_DH |
| Function | membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family |
| Trusted Cutoff | 832.65 |
| Domain Trusted Cutoff | 832.65 |
| Noise Cutoff | 552.25 |
| Domain Noise Cutoff | 552.25 |
| Isology Type | subfamily |
| EC Number | 1.1.-.- |
| HMM Length | 783 |
| Gene Ontology Term | GO:0016491: oxidoreductase activity molecular_function |
| | GO:0050662: coenzyme binding molecular_function |
| Author | Haft DH |
| Entry Date | Sep 20 2006 10:38AM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This protein family has a phylogenetic distribution very similar to that coenzyme PQQ biosynthesis enzymes, as shown by partial phylogenetic profiling. Members of this family have several predicted transmembrane helices in the N-terminal region, and include the quinoprotein glucose dehydrogenase (EC 1.1.5.2) of Escherichia coli and the quinate/shikimate dehydrogenase of Acinetobacter sp. ADP1 (EC 1.1.99.25). Sequences closely related except for the absense of the N-terminal hydrophobic region, scoring in the gray zone between the trusted and noise cutoffs, include PQQ-dependent glycerol (EC 1.1.99.22) and and other polyol (sugar alcohol) dehydrogenases. |
| References | DR PFAM; PF01011; PQQ enzyme repeat |
| Genome Property | GenProp0170: coenzyme PQQ biosynthesis (HMM) |
