|Function||holo-ACP synthase CitX|
|Domain Trusted Cutoff||105.25|
|Domain Noise Cutoff||57.15|
|Mainrole Category||Energy metabolism|
|Gene Ontology Term||GO:0050519: holo-citrate lyase synthase activity molecular_function|
| ||GO:0051191: prosthetic group biosynthetic process biological_process|
|Entry Date||Oct 28 2006 10:40PM|
|Last Modified||Feb 14 2011 3:27PM|
|Comment||Members of this protein family are the CitX protein, or CitX domain of the CitXG bifunctional protein, of the citrate lyase system. CitX transfers the prosthetic group 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA to the citrate lyase gamma chain, an acyl carrier protein. This enzyme may be designated holo-ACP synthase, holo-citrate lyase synthase, or apo-citrate lyase phosphoribosyl-dephospho-CoA transferase. In a few genera, including Haemophilus, this protein occurs as a fusion protein with CitG (220.127.116.11), an enzyme involved in prosthetic group biosynthesis. This CitX family is easily separated from the holo-ACP synthases of other enzyme systems.|
RM PMID: 11948157
RT Identification of a gene cluster in Klebsiella pneumoniae which includes citX, a gene required for biosynthesis of the citrate lyase prosthetic group.
RA Schneider K, Kastner CN, Meyer M, Wessel M, Dimroth P, Bott M
RL J Bacteriol. 2002 May;184(9):2439-46.
DR HAMAP; MF_00398; 18 of 19|
|Genome Property||GenProp0672: citrate lyase system (HMM)|
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