| Accession | TIGR03135 |
| Name | malonate_mdcG |
| Function | malonate decarboxylase holo-[acyl-carrier-protein] synthase |
| Gene Symbol | mdcG |
| Trusted Cutoff | 99.70 |
| Domain Trusted Cutoff | 99.70 |
| Noise Cutoff | 81.40 |
| Domain Noise Cutoff | 81.40 |
| Isology Type | equivalog |
| EC Number | 2.7.7.66 |
| HMM Length | 205 |
| Mainrole Category | Energy metabolism |
| Subrole Category | Other |
| Gene Ontology Term | GO:0050519: holo-citrate lyase synthase activity molecular_function |
| | GO:0051191: prosthetic group biosynthetic process biological_process |
| Author | Haft DH |
| Entry Date | Nov 1 2006 11:27AM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Malonate decarboxylase, like citrate lyase, has a unique acyl carrier protein subunit with a prosthetic group derived from, and distinct from, coenzyme A. Members of this protein family are the phosphoribosyl-dephospho-CoA transferase specific to the malonate decarboxylase system. This enzyme can also be designated holo-ACP synthase (2.7.7.61). The corresponding component of the citrate lyase system, CitX, shows little or no sequence similarity to this family. |
| References | RN [1]
RM PMID: 11052675
RT Biosynthesis of triphosphoribosyl-dephospho-coenzyme A, the precursor of the prosthetic group of malonate decarboxylase.
RA Hoenke S, Wild MR, Dimroth P
RL Biochemistry. 2000 Oct 31;39(43):13223-32. |
| Genome Property | GenProp0674: malonate decarboxylase (HMM) |
