HMM Summary Page: TIGR03142

Functioncytochrome c-type biogenesis protein CcmI
Gene SymbolccmI
Trusted Cutoff29.30
Domain Trusted Cutoff29.30
Noise Cutoff28.75
Domain Noise Cutoff28.75
Isology Typeequivalog_domain
HMM Length118
Mainrole CategoryProtein fate
Subrole CategoryProtein folding and stabilization
Gene Ontology TermGO:0017004: cytochrome complex assembly biological_process
GO:0051082: unfolded protein binding molecular_function
AuthorHaft DH
Entry DateNov 6 2006 8:44AM
Last ModifiedFeb 14 2011 3:27PM
CommentThis TPR repeat-containing protein is the CcmI protein (also called CycH) of c-type cytochrome biogenesis. CcmI is thought to act as an apo-cytochrome c chaperone. This model describes the N-terminal region of the protein, Members of this protein family
ReferencesRN [1] RM PMID: 15937187 RT Overproduction of CcmG and CcmFH(Rc) fully suppresses the c-type cytochrome biogenesis defect of Rhodobacter capsulatus CcmI-null mutants. RA Sanders C, Deshmukh M, Astor D, Kranz RG, Daldal F RL J Bacteriol. 2005 Jun;187(12):4245-56. RN [2] RM PMID: 14758542 RT The roles of different regions of the CycH protein in c-type cytochrome biogenesis in Sinorhizobium meliloti. RA Cinege G, Kereszt A, Kertesz S, Balogh G, Dusha I RL Mol Genet Genomics. 2004 Mar;271(2):171-9. Epub 2004 Jan 31. RN [3] RM PMID: 8752349 RT Rhodobacter capsulatus CycH: a bipartite gene product with pleiotropic effects on the biogenesis of structurally different c-type cytochromes. RA Lang SE, Jenney FE Jr, Daldal F RL J Bacteriol. 1996 Sep;178(17):5279-90.
Genome PropertyGenProp0678: c-type cytochrome biogenesis, system I (HMM)