HMM Summary Page: TIGR03153

Functioncytochrome c nitrite reductase, small subunit
Gene SymbolnrfH
Trusted Cutoff134.20
Domain Trusted Cutoff134.20
Noise Cutoff75.30
Domain Noise Cutoff75.30
Isology Typeequivalog
EC Number1.7.2.2
HMM Length138
Mainrole CategoryEnergy metabolism
Subrole CategoryElectron transport
AuthorHaft DH
Entry DateNov 10 2006 5:19PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family are NrfH, a tetraheme cytochrome c. NrfH is the cytochrome c nitrite reductase small subunit, and forms a heterodimer with NrfA, the catalytic subunit. While NrfA can act as a monomer, NrfH can bind to and anchor NrfA in the membrane and enables electron transfer to NrfA from quinones.
ReferencesRN [1] RM PMID: 11722563 RT The tetraheme cytochrome c NrfH is required to anchor the cytochrome c nitrite reductase (NrfA) in the membrane of Wolinella succinogenes. RA Simon J, Pisa R, Stein T, Eichler R, Klimmek O, Gross R RL Eur J Biochem. 2001 Nov;268(22):5776-82. RN [2] RM PMID: 10672190 RT A NapC/NirT-type cytochrome c (NrfH) is the mediator between the quinone pool and the cytochrome c nitrite reductase of Wolinella succinogenes. RA Simon J, Gross R, Einsle O, Kroneck PM, Kroger A, Klimmek O RL Mol Microbiol. 2000 Feb;35(3):686-96.
Genome PropertyGenProp0683: cytochrome c nitrite reductase NrfHA (HMM)