HMM Summary Page: TIGR03188

Functionphosphoribosyl-ATP diphosphatase
Gene SymbolhisE
Trusted Cutoff42.70
Domain Trusted Cutoff42.70
Noise Cutoff30.95
Domain Noise Cutoff30.95
Isology Typeequivalog_domain
EC Number3.6.1.31
HMM Length84
Mainrole CategoryAmino acid biosynthesis
Subrole CategoryHistidine family
Gene Ontology TermGO:0000105: histidine biosynthetic process biological_process
GO:0004636: phosphoribosyl-ATP diphosphatase activity molecular_function
AuthorHaft DH
Entry DateDec 6 2006 4:09PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis enzyme, phosphoribosyl-ATP pyrophosphohydrolase, catalyses the second step in the histidine biosynthesis pathway. It often occurs as a fusion protein. This model a somewhat narrower scope than Pfam model PF01503, as some paralogs that appear to be functionally distinct are excluded from this model.
ReferencesDR PFAM; PF01503; DR HAMAP; MF_01020; 209 of 210
Genome PropertyGenProp0109: histidine biosynthesis from ribose-5-phosphate (HMM)