HMM Summary Page: TIGR03216

Function2-hydroxymuconic semialdehyde dehydrogenase
Trusted Cutoff693.25
Domain Trusted Cutoff693.25
Noise Cutoff576.75
Domain Noise Cutoff576.75
Isology Typeequivalog
EC Number1.2.1.-
HMM Length481
Mainrole CategoryEnergy metabolism
Subrole CategoryOther
Gene Ontology TermGO:0016620: oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor molecular_function
AuthorHaft DH
Entry DateDec 18 2006 5:21PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family are 2-hydroxymuconic semialdehyde dehydrogenase. Many aromatic compounds are catabolized by way of the catechol, via the meta-cleavage pathway, to pyruvate and acetyl-CoA. This enzyme performs the second of seven steps in that pathway for catechol degradation.
Genome PropertyGenProp0708: catechol meta-cleavage pathway (HMM)