HMM Summary Page: TIGR03218
| Accession | TIGR03218 |
| Name | catechol_dmpH |
| Function | 4-oxalocrotonate decarboxylase |
| Gene Symbol | dmpH |
| Trusted Cutoff | 350.55 |
| Domain Trusted Cutoff | 350.55 |
| Noise Cutoff | 294.20 |
| Domain Noise Cutoff | 294.20 |
| Isology Type | equivalog |
| EC Number | 4.1.1.77 |
| HMM Length | 263 |
| Mainrole Category | Energy metabolism |
| Subrole Category | Other |
| Gene Ontology Term | GO:0047437: 4-oxalocrotonate decarboxylase activity molecular_function |
| Author | Haft DH |
| Entry Date | Dec 19 2006 2:40PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Members of this protein family are 4-oxalocrotonate decarboxylase. Note that this protein, as characterized (indirectly) in Pseudomonas sp. strain CF600, was inactive except when coexpressed with DmpE, 2-oxopent-4-enoate hydratase, a homologous protein from the same operon. Both of these enzymes are active in the degradation of catechol, a common intermediate in the degradation of aromatic compounds such as benzoate, toluene, phenol, dimethylphenol (dmp), salicylate, etc. |
| References | RN [1] RM PMID: 1732207 RT Nucleotide sequence and functional analysis of the complete phenol/3,4-dimethylphenol catabolic pathway of Pseudomonas sp. strain CF600. RA Shingler V, Powlowski J, Marklund U RL J Bacteriol. 1992 Feb;174(3):711-24. |
| Genome Property | GenProp0708: catechol meta-cleavage pathway (HMM) |