HMM Summary Page: TIGR03224

Functionbenzoyl-CoA oxygenase/reductase, BoxA protein
Gene SymbolboxA
Trusted Cutoff459.20
Domain Trusted Cutoff459.20
Noise Cutoff260.80
Domain Noise Cutoff260.80
Isology Typeequivalog
EC Number1.14.12.21
HMM Length411
Mainrole CategoryEnergy metabolism
Subrole CategoryOther
Gene Ontology TermGO:0010128: benzoate catabolic process via CoA ligation biological_process
GO:0051213: dioxygenase activity molecular_function
AuthorHaft DH
Entry DateDec 21 2006 2:36PM
Last ModifiedDec 12 2011 11:07PM
CommentMembers of this protein family are BoxA, the A component of the BoxAB benzoyl-CoA oxygenase/reductase. This oxygen-requiring enzyme acts in an aerobic pathway of benzoate catabolism via coenzyme A ligation. BoxA is a homodimeric iron-sulphur-flavoprotein and acts as an NADPH-dependent reductase for BoxB.
ReferencesRN [1] RM PMID: 15458418 RT New enzymes involved in aerobic benzoate metabolism in Azoarcus evansii. RA Zaar A, Gescher J, Eisenreich W, Bacher A, Fuchs G RL Mol Microbiol. 2004 Oct;54(1):223-38. RN [2] RM PMID: 15916608 RT Aerobic benzoyl-CoA catabolic pathway in Azoarcus evansii: studies on the non-oxygenolytic ring cleavage enzyme. RA Gescher J, Eisenreich W, Worth J, Bacher A, Fuchs G RL Mol Microbiol. 2005 Jun;56(6):1586-600.
Genome PropertyGenProp0709: benzoate catabolism BoxABC pathway (HMM)