Accession | TIGR03228 |
Name | anthran_1_2_A |
Function | anthranilate 1,2-dioxygenase, large subunit |
Gene Symbol | antA |
Trusted Cutoff | 671.90 |
Domain Trusted Cutoff | 671.90 |
Noise Cutoff | 671.65 |
Domain Noise Cutoff | 671.65 |
Isology Type | equivalog |
EC Number | 1.14.12.1 |
HMM Length | 438 |
Mainrole Category | Energy metabolism |
Subrole Category | Amino acids and amines |
Gene Ontology Term | GO:0006569: tryptophan catabolic process biological_process |
| GO:0018618: anthranilate 1,2-dioxygenase (deaminating, decarboxylating) activity molecular_function |
Author | Haft DH |
Entry Date | Dec 27 2006 10:58AM |
Last Modified | Feb 14 2011 3:27PM |
Comment | Anthranilate (2-aminobenzoate) is an intermediate of tryptophan (Trp) biosynthesis and degradation. Members of this family are the large subunit of anthranilate 1,2-dioxygenase, which acts in Trp degradation by converting anthranilate to catechol. Closely related paralogs typically are the benzoate 1,2-dioxygenase large subunit, among the larger set of ring-hydroxylating dioxygenases. |
References | RN [1]
RM PMID: 11114907
RT Characterization and evolution of anthranilate 1,2-dioxygenase from Acinetobacter sp. strain ADP1.
RA Eby DM, Beharry ZM, Coulter ED, Kurtz DM Jr, Neidle EL
RL J Bacteriol. 2001 Jan;183(1):109-18. |