| Accession | TIGR03249 |
| Name | KdgD |
| Function | 5-dehydro-4-deoxyglucarate dehydratase |
| Gene Symbol | kdgD |
| Trusted Cutoff | 373.95 |
| Domain Trusted Cutoff | 373.95 |
| Noise Cutoff | 332.85 |
| Domain Noise Cutoff | 332.85 |
| Isology Type | equivalog |
| EC Number | 4.2.1.41 |
| HMM Length | 299 |
| Author | Selengut J |
| Entry Date | Jan 10 2007 1:17PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | 5-dehydro-4-deoxyglucarate dehydratase not only catalyzes the dehydration of the substrate (diol to ketone + water), but causes the decarboxylation of the intermediate product to yield 2-oxoglutarate semialdehyde (2,5-dioxopentanoate). The gene for the enzyme is usually observed in the vicinity of transporters and dehydratases handling D-galactarate and D-gluconate as well as aldehyde dehydrogenases which convert the product to alpha-ketoglutarate. |
| Genome Property | GenProp0715: galactarate utilization via 2-oxoglutarate semialdehyde (HMM) |
| | GenProp0717: glucarate utilization via 2-oxoglutarate semialdehyde (HMM) |
