| Accession | TIGR03253 |
| Name | oxalate_frc |
| Function | formyl-CoA transferase |
| Gene Symbol | frc |
| Trusted Cutoff | 504.20 |
| Domain Trusted Cutoff | 504.20 |
| Noise Cutoff | 371.30 |
| Domain Noise Cutoff | 371.30 |
| Isology Type | equivalog |
| EC Number | 2.8.3.16 |
| HMM Length | 416 |
| Mainrole Category | Cellular processes |
| Subrole Category | Detoxification |
| Gene Ontology Term | GO:0005515: protein binding molecular_function |
| | GO:0009636: response to toxin biological_process |
| | GO:0033608: formyl-CoA transferase activity molecular_function |
| | GO:0033611: oxalate catabolic process biological_process |
| Author | Haft DH |
| Entry Date | Jan 12 2007 11:23AM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This enzyme, formyl-CoA transferase, transfers coenzyme A from formyl-CoA to oxalate. It forms a pathway, together with oxalyl-CoA decarboxylase, for oxalate degradation; decarboxylation by the latter gene regenerates formyl-CoA. The two enzymes typically are encoded by a two-gene operon. |
| References | RN [1]
RM PMID: 16517636
RT Transcriptional and functional analysis of oxalyl-coenzyme A (CoA) decarboxylase and formyl-CoA transferase genes from Lactobacillus acidophilus.
RA Azcarate-Peril MA, Bruno-Barcena JM, Hassan HM, Klaenhammer TR
RL Appl Environ Microbiol. 2006 Mar;72(3):1891-9.
RN [2]
RM PMID: 12844490
RT The crystal structure of the Escherichia coli YfdW gene product reveals a new fold of two interlaced rings identifying a wide family of CoA transferases.
RA Gruez A, Roig-Zamboni V, Valencia C, Campanacci V, Cambillau C
RL J Biol Chem. 2003 Sep 5;278(36):34582-6. Epub 2003 Jul 3. |
| Genome Property | GenProp0718: oxalate degradation (HMM) |
