|Domain Trusted Cutoff||360.80|
|Domain Noise Cutoff||290.05|
|Entry Date||Feb 1 2007 1:38PM|
|Last Modified||Feb 14 2011 3:27PM|
|Comment||This family includes a number of 2-aminoethylphosphonate aminotransferases, some of which are indicated to operate in the catabolism of 2-aminoethylphosphonate (AEP) and others which are involved in the biosynthesis of the same compound. The catabolic enzyme (PhnW, ) is known to use pyruvate:alanine as the transfer partner and is modeled by the equivalog-level HMM (TIGR02326). The PhnW family is apparently a branch of a larger tree including genes (AepZ) adjacent to others responsible for the biosynthesis of phosphonoacetaldehyde . The identity of the transfer partner is unknown for these enzymes and considering the reversed flux compared to PhnW, it may very well be different.|
RM PMID: 12107130
RT The 2-aminoethylphosphonate-specific transaminase of the 2-aminoethylphosphonate degradation pathway.
RA Kim AD, Baker AS, Dunaway-Mariano D, Metcalf WW, Wanner BL, Martin BM
RL J Bacteriol. 2002 Aug;184(15):4134-40.
RM PMID: 11035722
RT Bacteroides fragilis NCTC9343 produces at least three distinct capsular polysaccharides: cloning, characterization, and reassignment of polysaccharide B and C biosynthesis loci.
RA Coyne MJ, Kalka-Moll W, Tzianabos AO, Kasper DL, Comstock LE
RL Infect Immun. 2000 Nov;68(11):6176-81.|
|Genome Property||GenProp0724: phosphonoacetaldehyde biosynthesis from phosphoenolpyruvate (SUBFAMILY)|
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