| Accession | TIGR03304 |
| Name | OMP85_target |
| Function | outer membrane insertion C-terminal signal |
| Trusted Cutoff | 0.00 |
| Domain Trusted Cutoff | 0.00 |
| Noise Cutoff | 0.00 |
| Domain Noise Cutoff | 0.00 |
| Isology Type | domain |
| HMM Length | 10 |
| Gene Ontology Term | GO:0019867: outer membrane cellular_component |
| Author | Haft DH |
| Entry Date | Feb 6 2007 12:41PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This hidden Markov model detects a 10-residue targeting sequence common to beta-barrel outer membrane proteins (OMP) that rely on Omp85-like proteins for insertion into the outer membrane. Hits should be trusted if they include the last amino acid of a protein sequence that occurs in Gram-negative bacteria. It has been noted that Omp85 target sequences differ somewhat by species, while this model works generally for most Proteobacteria. For a given species, an iterated approach, in which trusted matches to this model become the basis of a new model that finds additional OMP signals, is recommended. |
| References | RN [1]
RM PMID: 17090219
RT Assembly factor Omp85 recognizes its outer membrane protein substrates by a species-specific C-terminal motif.
RA Robert V, Volokhina EB, Senf F, Bos MP, Van Gelder P, Tommassen J
RL PLoS Biol. 2006 Nov;4(11):e377. |
| Genome Property | GenProp0725: outer membrane protein assembly complex (HMM) |
