| Accession | TIGR03310 |
| Name | matur_MocA_YgfJ |
| Function | molybdenum cofactor cytidylyltransferase |
| Gene Symbol | mocA |
| Trusted Cutoff | 186.45 |
| Domain Trusted Cutoff | 186.45 |
| Noise Cutoff | 182.80 |
| Domain Noise Cutoff | 182.80 |
| Isology Type | equivalog |
| EC Number | 2.7.7.76 |
| HMM Length | 188 |
| Author | Haft DH |
| Entry Date | Feb 13 2007 3:49PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Members of this protein include MocA, which transfers cytosine from CTP to molybdopterin during molybdopterin cytosine dinucleotide (MCD) cofactor biosynthesis. It is distantly related to MobA, the GTP:molybdopterin guanylyltransferase. The MocA family is particularly closely related in phylogenetic distribution to other markers of selenium-dependent molybdenum hydroxylases (SDMH), suggesting most SDMH must use MCD rather than molybdopterin guanine dinucleotide. |
| References | RN [1]
RM PMID:18289380
RT Orphan SelD proteins and selenium-dependent molybdenum hydroxylases.
RA Haft DH, Self WT
RL Biol Direct. 2008 Feb 20;3:4.
RN [2]
RM PMID:19542235
RT MocA is a specific cytidylyltransferase involved in molybdopterin cytosine dinucleotide biosynthesis in Escherichia coli.
RA Neumann M, Mittelstadt G, Seduk F, Iobbi-Nivol C, Leimkuhler S
RL J Biol Chem. 2009 Aug 14;284(33):21891-8. |
| Genome Property | GenProp0726: selenium-dependent molybdenum hydroxylase system (HMM) |
