| Accession | TIGR03341 |
| Name | YhgI_GntY |
| Function | IscR-regulated protein YhgI |
| Gene Symbol | yhgI |
| Trusted Cutoff | 269.35 |
| Domain Trusted Cutoff | 269.35 |
| Noise Cutoff | 97.85 |
| Domain Noise Cutoff | 97.85 |
| Isology Type | hypoth_equivalog |
| HMM Length | 190 |
| Mainrole Category | Biosynthesis of cofactors, prosthetic groups, and carriers |
| Subrole Category | Other |
| Gene Ontology Term | GO:0003674: molecular_function molecular_function |
| | GO:0016226: iron-sulfur cluster assembly biological_process |
| Author | Haft DH |
| Entry Date | Mar 12 2007 4:13PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | IscR (TIGR02010) is an iron-sulfur cluster-binding transcriptional regulator (see Genome Property GenProp0138). Members of this protein family include YhgI, whose expression is under control of IscR, and show sequence similarity to IscA, a known protein of iron-sulfur cluster biosynthesis. These two lines of evidence strongly suggest a role as an iron-sulfur cluster biosynthesis protein. An older study designated this protein GntY and suggested a role for it and for the product of an adjacent gene, based on complementation studies, in gluconate utilization. |
| References | DR PF01521; Fe-S_biosyn; HesB-like domain
RN [1]
RM PMID: 16677314
RT IscR-dependent gene expression links iron-sulphur cluster assembly to the control of O2-regulated genes in Escherichia coli.
RA Giel JL, Rodionov D, Liu M, Blattner FR, Kiley PJ
RL Mol Microbiol. 2006 May;60(4):1058-75.
RN [2]
RM PMID: 9871335
RT The gluconate high affinity transport of GntI in Escherichia coli involves a multicomponent complex system.
RA Porco A, Alonso G, Isturiz T
RL J Basic Microbiol. 1998;38(5-6):395-404. |
