| Accession | TIGR03349 |
| Name | IV_VI_DotU |
| Function | type IV/VI secretion system protein, DotU family |
| Trusted Cutoff | 89.95 |
| Domain Trusted Cutoff | 89.95 |
| Noise Cutoff | 51.40 |
| Domain Noise Cutoff | 51.40 |
| Isology Type | subfamily_domain |
| HMM Length | 211 |
| Mainrole Category | Protein fate |
| Subrole Category | Protein and peptide secretion and trafficking |
| Gene Ontology Term | GO:0003674: molecular_function molecular_function |
| | GO:0052048: interaction with host via secreted substance involved in symbiotic interaction biological_process |
| Author | Haft DH |
| Entry Date | Mar 15 2007 9:31AM |
| Last Modified | Aug 24 2011 4:15PM |
| Comment | At least two families of proteins, often encoded by adjacent genes, show sequence similarity due to homology between type IV secretion systems and type VI secretion systems. One is the IcmF family (TIGR03348). The other is the family described by this model. Members include DotU from the Legionella pneumophila type IV secretion system. Many of the members of this protein family from type VI secretion systems have an additional C-terminal domain with OmpA/MotB homology. |
| References | RN [1]
RM PMID: 16763151
RT A virulence locus of Pseudomonas aeruginosa encodes a protein secretion apparatus.
RA Mougous JD, Cuff ME, Raunser S, Shen A, Zhou M, Gifford CA, Goodman AL, Joachimiak G, Ordonez CL, Lory S, Walz T, Joachimiak A, Mekalanos JJ
RL Science. 2006 Jun 9;312(5779):1526-30. |
| Genome Property | GenProp0735: type VI secretion (HMM) |
