HMM Summary Page: TIGR03368

Functioncellulose synthase operon protein YhjU
Gene SymbolyhjU
Trusted Cutoff410.20
Domain Trusted Cutoff410.20
Noise Cutoff208.50
Domain Noise Cutoff208.50
Isology Typehypoth_equivalog
HMM Length518
Mainrole CategoryCell envelope
Subrole CategoryBiosynthesis and degradation of surface polysaccharides and lipopolysaccharides
Gene Ontology TermGO:0003674: molecular_function molecular_function
GO:0005575: cellular_component cellular_component
GO:0030244: cellulose biosynthetic process biological_process
AuthorHaft DH
Entry DateMar 22 2007 4:31PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis protein was identified by the partial phylogenetic profiling algorithm (PMID:16930487) as part of the system for cellulose biosynthesis in bacteria, and in fact is found in cellulose biosynthesis gene regions. The protein was designated YhjU in Salmonella enteritidis, where disruption of its gene disrupts cellulose biosynthesis and biofilm formation (PMID:11929533).
ReferencesRN [1] RM PMID: 11929533 RT Genetic analysis of Salmonella enteritidis biofilm formation: critical role of cellulose. RA Solano C, Garcia B, Valle J, Berasain C, Ghigo JM, Gamazo C, Lasa I RL Mol Microbiol. 2002 Feb;43(3):793-808. RN [2] RM PMID: 16930487 RT Exopolysaccharide-associated protein sorting in environmental organisms: the PEP-CTERM/EpsH system. Application of a novel phylogenetic profiling heuristic. RA Haft DH, Paulsen IT, Ward N, Selengut JD RL BMC Biol. 2006 Aug 24;4:29.
Genome PropertyGenProp0658: cellulose biosynthesis (HMM)