HMM Summary Page: TIGR03379

AccessionTIGR03379
Nameglycerol3P_GlpC
Functionglycerol-3-phosphate dehydrogenase, anaerobic, C subunit
Gene SymbolglpC
Trusted Cutoff279.90
Domain Trusted Cutoff279.90
Noise Cutoff222.45
Domain Noise Cutoff222.45
Isology Typeequivalog
EC Number1.1.5.3
HMM Length397
Mainrole CategoryEnergy metabolism
Subrole CategoryAnaerobic
Gene Ontology TermGO:0006071: glycerol metabolic process biological_process
GO:0006071: glycerol metabolic process biological_process
GO:0009331: glycerol-3-phosphate dehydrogenase complex cellular_component
GO:0009331: glycerol-3-phosphate dehydrogenase complex cellular_component
GO:0051536: iron-sulfur cluster binding molecular_function
GO:0051536: iron-sulfur cluster binding molecular_function
AuthorHaft DH
Entry DateApr 2 2007 4:05PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family are the membrane-anchoring, non-catalytic C subunit, product of the glpC gene, of a three-subunit, FAD-dependent, anaerobic glycerol-3-phosphate dehydrogenase. GlpC lasks classical hydrophobic transmembrane helices; Cole, et al suggest interaction with the membrane may involve amphipathic helices. GlcC has conserved Cys-containing motifs suggestive of iron-sulfur binding. This complex is found mostly in Escherichia coli and closely related species.
ReferencesRN [1] RM PMID: 3286606 RT Nucleotide sequence and gene-polypeptide relationships of the glpABC operon encoding the anaerobic sn-glycerol-3-phosphate dehydrogenase of Escherichia coli K-12. RA Cole ST, Eiglmeier K, Ahmed S, Honore N, Elmes L, Anderson WF, Weiner JH RL J Bacteriol. 1988 Jun;170(6):2448-56.
Genome PropertyGenProp0737: anaerobic glycerol-3-phosphate dehydrogenase complex (HMM)
GenProp0737: anaerobic glycerol-3-phosphate dehydrogenase complex (HMM)