HMM Summary Page: TIGR03380

Functionagmatine deiminase
Gene SymbolaguA
Trusted Cutoff381.80
Domain Trusted Cutoff381.80
Noise Cutoff309.30
Domain Noise Cutoff309.30
Isology Typeequivalog
EC Number3.5.3.12
HMM Length357
Mainrole CategoryCentral intermediary metabolism
Subrole CategoryPolyamine biosynthesis
Gene Ontology TermGO:0005737: cytoplasm cellular_component
GO:0009446: putrescine biosynthetic process biological_process
GO:0047632: agmatine deiminase activity molecular_function
AuthorHaft DH, Harkins DM
Entry DateApr 6 2007 3:10PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this family are agmatine deiminase (, as characterized in Pseudomonas aeruginosa and plants. Related deiminases include the peptidyl-arginine deiminase ( as found in Porphyromonas gingivalis.
ReferencesRN [1] RM PMID: 12634339 RT Identification of the putrescine biosynthetic genes in Pseudomonas aeruginosa and characterization of agmatine deiminase and N-carbamoylputrescine amidohydrolase of the arginine decarboxylase pathway. RA Nakada Y, Itoh Y RL Microbiology. 2003 Mar;149(Pt 3):707-14. RN [2] RM PMID: 12782327 RT Identification and characterization of plant agmatine iminohydrolase, the last missing link in polyamine biosynthesis of plants. RA Janowitz T, Kneifel H, Piotrowski M RL FEBS Lett. 2003 Jun 5;544(1-3):258-61.
Genome PropertyGenProp0738: agmatine to putrescine via N-carbamoylputrescine (HMM)