HMM Summary Page: TIGR03382

FunctionMyxococcales GC_trans_RRR domain
Trusted Cutoff15.85
Domain Trusted Cutoff15.85
Noise Cutoff14.85
Domain Noise Cutoff14.85
Isology Typedomain
HMM Length27
AuthorHaft DH
Entry DateApr 16 2007 10:58AM
Last ModifiedApr 12 2012 5:43PM
CommentThe domain described here is small (about 30 amino acids), hydrophobic, only moderately conserved, and similar to numerous other transmembrane helix-containing sequence regions from convergent evolution. The trusted cutoff for the HMM therefore must be set fairly high. This domain is found, once per protein but in many proteins per genome in several bacteria of the order Myxococcales. It begins with a signature Gly-Cys motif. Its other features, including a hydrophobic transmembrane helix, Arg-rich cluster, and location at the protein C-terminus, resemble the PEP-CTERM proposed protein targeting domain.
Genome PropertyGenProp0960: protein sorting system, MYXO-CTERM/unknown of Deltaproteobacteria (HMM)