HMM Summary Page: TIGR03399

AccessionTIGR03399
NameRNA_3prim_cycl
FunctionRNA 3'-phosphate cyclase
Gene SymbolrtcA
Trusted Cutoff250.05
Domain Trusted Cutoff250.05
Noise Cutoff146.10
Domain Noise Cutoff146.10
Isology Typeequivalog
EC Number6.5.1.4
HMM Length326
Mainrole CategoryTranscription
Subrole CategoryRNA processing
Gene Ontology TermGO:0003963: RNA-3'-phosphate cyclase activity molecular_function
GO:0003963: RNA-3'-phosphate cyclase activity molecular_function
GO:0006396: RNA processing biological_process
GO:0006396: RNA processing biological_process
AuthorHaft DH
Entry DateApr 26 2007 3:32PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family are RNA 3'-phosphate cyclase (6.5.1.4), an enzyme whose function is conserved from E. coli to human. The modification this enzyme performs enables certain RNA ligations to occur, although the full biological roll for this enzyme is not fully described. This model separates this enzyme from a related protein, present only in eukaryotes, localized to the nucleolus, and involved in ribosomal modification.
ReferencesDR PFAM; PF05189; RTC_insert DR PFAM; PF01137; RTC