HMM Summary Page: TIGR03412

FunctionFeS assembly protein IscX
Gene SymboliscX
Trusted Cutoff40.40
Domain Trusted Cutoff40.40
Noise Cutoff24.95
Domain Noise Cutoff24.95
Isology Typeequivalog
HMM Length63
Mainrole CategoryBiosynthesis of cofactors, prosthetic groups, and carriers
Subrole CategoryOther
Gene Ontology TermGO:0005506: iron ion binding molecular_function
GO:0016226: iron-sulfur cluster assembly biological_process
AuthorHaft DH
Entry DateMay 16 2007 12:47PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family are YfhJ, a protein of the ISC system for iron-sulfur cluster assembly. Other genes in the system include iscSUA, hscBA, and fdx.
ReferencesRN [1] RM PMID: 16698547 RT YfhJ, a molecular adaptor in iron-sulfur cluster formation or a frataxin-like protein? RA Pastore C, Adinolfi S, Huynen MA, Rybin V, Martin S, Mayer M, Bukau B, Pastore A RL Structure. 2006 May;14(5):857-67. RN [2] RM PMID: 15937904 RT Crystal structure of Escherichia coli YfhJ protein, a member of the ISC machinery involved in assembly of iron-sulfur clusters. RA Shimomura Y, Takahashi Y, Kakuta Y, Fukuyama K RL Proteins. 2005 Aug 15;60(3):566-9.
Genome PropertyGenProp0138: iron-sulfur cluster assembly iscSUA-hscBA-fdx system (HMM)