| Accession | TIGR03426 |
| Name | shape_MreD |
| Function | rod shape-determining protein MreD |
| Gene Symbol | mreD |
| Trusted Cutoff | 34.85 |
| Domain Trusted Cutoff | 34.85 |
| Noise Cutoff | 27.15 |
| Domain Noise Cutoff | 27.15 |
| Isology Type | equivalog |
| HMM Length | 154 |
| Mainrole Category | Cell envelope |
| Subrole Category | Biosynthesis and degradation of murein sacculus and peptidoglycan |
| Gene Ontology Term | GO:0003674: molecular_function molecular_function |
| | GO:0008360: regulation of cell shape biological_process |
| Author | Haft DH |
| Entry Date | Jun 12 2007 2:46PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Members of this protein family are the MreD protein of bacterial cell shape determination. Most rod-shaped bacteria depend on MreB and RodA to achieve either a rod shape or some other non-spherical morphology such as coil or stalk formation. MreD is encoded in an operon with MreB, and often with RodA and PBP-2 as well. It is highly hydrophobic (therefore somewhat low-complexity) and highly divergent, and therefore sometimes tricky to discover by homology, but this model finds most examples. |
| Genome Property | GenProp0166: mreBCD system (HMM) |
