HMM Summary Page: TIGR03434

Functionacidobacterial duplicated orphan permease
Trusted Cutoff622.30
Domain Trusted Cutoff622.30
Noise Cutoff303.15
Domain Noise Cutoff303.15
Isology Typeparalog
HMM Length803
Gene Ontology TermGO:0003674: molecular_function molecular_function
GO:0005887: integral to plasma membrane cellular_component
GO:0006810: transport biological_process
AuthorHaft DH
Entry DateJun 15 2007 9:15AM
Last ModifiedMar 1 2011 11:50AM
CommentMembers of this protein family are found, so far, only in three species of Acidobacteria, namely Acidobacteria bacterium Ellin345, Acidobacterium capsulatum ATCC 51196, and Solibacter usitatus Ellin6076, where they form large paralogous families. Each protein contains two copies of a domain called the efflux ABC transporter permease protein (PF02687). However, unlike other members of that family (including LolC, FtsX, and MacB), genes for these proteins are essentially never found fused or adjacent to ABC transporter ATP-binding protein (PF00005) genes. We name this family ADOP, for Acidobacterial Duplicated Orphan Permease, to reflect the restricted lineage, internal duplication, lack of associated ATP-binding cassette proteins, and permease homology. The function is unknown.
Genome PropertyGenProp0751: Acidobacterial ADOP/PadR gene pairs (HMM)