HMM Summary Page: TIGR03520

Functiongliding motility-associated protein GldE
Gene SymbolgldE
Trusted Cutoff376.05
Domain Trusted Cutoff376.05
Noise Cutoff329.20
Domain Noise Cutoff329.20
Isology Typesubfamily
HMM Length408
AuthorSelengut J
Entry DateDec 17 2007 10:25AM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family are exclusive to the Bacteroidetes phylum (previously Cytophaga-Flavobacteria-Bacteroides). GldC is a protein linked to a type of rapid surface gliding motility found in certain Bacteroidetes, such as Flavobacterium johnsoniae and Cytophaga hutchinsonii. GldE was discovered because of its adjacency to GldD in F. johnsonii. Overexpression of GldE partially supresses the effects of a GldB point mutant suggesting that GldB and GldE interact [1]. Gliding motility appears closely linked to chitin utilization in the model species Flavobacterium johnsoniae. Not all Bacteroidetes with members of this protein family appear to have all of the genes associated with gliding motility and in fact some do not appear to express the gliding phenotype.
ReferencesRN [1] RM PMID:11418556 RT Cloning and characterization of the Flavobacterium johnsoniae gliding motility genes gldD and gldE. RA Hunnicutt DW, McBride MJ RL J Bacteriol. 2001 Jul;183(14):4167-75.
Genome PropertyGenProp0781: gliding motility, Bacteroidetes type (HMM)