HMM Summary Page: TIGR03525

Functiongliding motility-associated lipoprotein GldK
Gene SymbolgldK
Trusted Cutoff487.10
Domain Trusted Cutoff487.10
Noise Cutoff164.45
Domain Noise Cutoff164.45
Isology Typeequivalog
HMM Length449
AuthorSelengut J
Entry DateDec 18 2007 3:00PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family are exclusive to the Bacteroidetes phylum (previously Cytophaga-Flavobacteria-Bacteroides). GldK is a lipoprotein linked to a type of rapid surface gliding motility found in certain Bacteroidetes, such as Flavobacterium johnsoniae [1]. Knockouts of GldK abolish the gliding phenotype. GldK is homologous to GldJ [2]. There is a GldK homolog in Cytophaga hutchinsonii and several other species that has a different, shorter architecture and is represented by a separate model. Gliding motility appears closely linked to chitin utilization in the model species Flavobacterium johnsoniae. Bacteroidetes with members of this protein family appear to have all of the genes associated with gliding motility.
ReferencesRN [1] RM PMID:16199564 RT Flavobacterium johnsoniae gliding motility genes identified by mariner mutagenesis. RA Braun TF, Khubbar MK, Saffarini DA, McBride MJ RL J Bacteriol. 2005 Oct;187(20):6943-52. RN [2] RM PMID:15805509 RT Flavobacterium johnsoniae GldJ is a lipoprotein that is required for gliding motility. RA Braun TF, McBride MJ RL J Bacteriol. 2005 Apr;187(8):2628-37.
Genome PropertyGenProp0781: gliding motility, Bacteroidetes type (HMM)