HMM Summary Page: TIGR03529

Functiongliding motility-associated lipoprotein GldK
Gene SymbolgldK
Trusted Cutoff584.10
Domain Trusted Cutoff584.10
Noise Cutoff359.80
Domain Noise Cutoff359.80
Isology Typeequivalog
HMM Length345
AuthorSelengut J
Entry DateDec 21 2007 9:19AM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family are exclusive to the Bacteroidetes phylum (previously Cytophaga-Flavobacteria-Bacteroides). GldK is a lipoprotein linked to a type of rapid surface gliding motility found in certain Bacteroidetes, such as Flavobacterium johnsoniae [1]. Knockouts of GldK abolish the gliding phenotype. GldK is homologous to GldJ [2]. This model represents a GldK homolog in Cytophaga hutchinsonii and several other species that has a different, shorter architecture than that found in Flavobacterium johnsoniae and related species (represented by (TIGR03525). Gliding motility appears closely linked to chitin utilization in the model species Flavobacterium johnsoniae. Bacteroidetes with members of this protein family appear to have all of the genes associated with gliding motility.
ReferencesRN [1] RM PMID:16199564 RT Flavobacterium johnsoniae gliding motility genes identified by mariner mutagenesis. RA Braun TF, Khubbar MK, Saffarini DA, McBride MJ RL J Bacteriol. 2005 Oct;187(20):6943-52. RN [2] RM PMID:15805509 RT Flavobacterium johnsoniae GldJ is a lipoprotein that is required for gliding motility. RA Braun TF, McBride MJ RL J Bacteriol. 2005 Apr;187(8):2628-37.
Genome PropertyGenProp0781: gliding motility, Bacteroidetes type (HMM)