| Accession | TIGR03550 |
| Name | F420_cofG |
| Function | 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofG subunit |
| Gene Symbol | cofG |
| Trusted Cutoff | 213.35 |
| Domain Trusted Cutoff | 213.35 |
| Noise Cutoff | 106.85 |
| Domain Noise Cutoff | 106.85 |
| Isology Type | equivalog_domain |
| EC Number | 2.5.1.77 |
| HMM Length | 322 |
| Mainrole Category | Biosynthesis of cofactors, prosthetic groups, and carriers |
| Subrole Category | Other |
| Gene Ontology Term | GO:0009108: coenzyme biosynthetic process biological_process |
| Author | Haft DH |
| Entry Date | Feb 29 2008 2:25PM |
| Last Modified | Dec 12 2011 10:10PM |
| Comment | This model represents either a subunit or a domain, depending on whether or not the genes are fused, of a bifunctional protein that completes the synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin, or FO. FO is the chromophore of coenzyme F(420), involved in methanogenesis in methanogenic archaea but found in certain other lineages as well. The chromophore also occurs as a cofactor in DNA photolyases in Cyanobacteria. |
| References | RN [1]
RM PMID:14593448
RT Identification of the 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase required for coenzyme F(420) biosynthesis.
RA Graham DE, Xu H, White RH
RL Arch Microbiol. 2003 Dec;180(6):455-64. Epub 2003 Oct 31. |
| Genome Property | GenProp0792: 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) biosynthesis (HMM) |
