| Accession | TIGR03585 |
| Name | PseH |
| Function | pseudaminic acid biosynthesis N-acetyl transferase |
| Gene Symbol | pseH |
| Trusted Cutoff | 93.10 |
| Domain Trusted Cutoff | 93.10 |
| Noise Cutoff | 81.60 |
| Domain Noise Cutoff | 81.60 |
| Isology Type | hypoth_equivalog |
| HMM Length | 156 |
| Author | Selengut J |
| Entry Date | Apr 8 2008 5:17PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Sequences in this family are members of the PF00583 (GNAT) superfamily of acetyltransferases and are proposed to perform a N-acetylation step in the process of pseudaminic acid biosynthesis in Campylobacter species [1]. This gene is commonly observed in apparent operons with other genes responsible for the biosynthesis of pseudaminic acid and as a component of flagellar and exopolysaccharide biosynthesis loci. Significantly, many genomes containing other components of this pathway lack this gene, indicating that some other N-acetyl transferases may be incolved and/or the step is optional, resulting in a non-acetylated pseudaminic acid variant sugar. |
| References | RN [1]
RM PMID:16684771
RT Functional characterization of the flagellar glycosylation locus in Campylobacter jejuni 81-176 using a focused metabolomics approach.
RA McNally DJ, Hui JP, Aubry AJ, Mui KK, Guerry P, Brisson JR, Logan SM, Soo EC
RL J Biol Chem. 2006 Jul 7;281(27):18489-98. Epub 2006 May 9. |
| Genome Property | GenProp0796: CMP-pseudaminic acid biosynthesis from UDP-N-acetylglucosamine (HMM) |
