HMM Summary Page: TIGR03596

Functionribosome biogenesis GTP-binding protein YlqF
Gene SymbolylqF
Trusted Cutoff208.20
Domain Trusted Cutoff208.20
Noise Cutoff207.25
Domain Noise Cutoff207.25
Isology Typeequivalog
HMM Length276
Mainrole CategoryProtein synthesis
Subrole CategoryOther
Gene Ontology TermGO:0003924: GTPase activity molecular_function
GO:0005525: GTP binding molecular_function
GO:0005737: cytoplasm cellular_component
GO:0042254: ribosome biogenesis biological_process
AuthorHaft DH
Entry DateApr 17 2008 8:27AM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family are GTP-binding proteins involved in ribosome biogenesis, including the essential YlqF protein of Bacillus subtilis, which is an essential protein. They are related to Era, EngA, and other GTPases of ribosome biogenesis, but are circularly permuted. This family is not universal, and is not present in Escherichia coli, and so is not as well studied as some other GTPases. This model is built for bacterial members.
ReferencesRN [1] RM PMID:17613524 RT Isolation and characterization of a dominant negative mutant of Bacillus subtilis GTP-binding protein, YlqF, essential for biogenesis and maintenance of the 50 S ribosomal subunit. RA Matsuo Y, Oshima T, Loh PC, Morimoto T, Ogasawara N RL J Biol Chem. 2007 Aug 31;282(35):25270-7.
Genome PropertyGenProp0802: ribosome biogenesis proteins, bacteria (HMM)