HMM Summary Page: TIGR03598

Functionribosome biogenesis GTP-binding protein YsxC
Gene SymbolysxC
Trusted Cutoff124.45
Domain Trusted Cutoff124.45
Noise Cutoff102.80
Domain Noise Cutoff102.80
Isology Typeequivalog
HMM Length186
Mainrole CategoryProtein synthesis
Subrole CategoryOther
Gene Ontology TermGO:0003924: GTPase activity molecular_function
GO:0005525: GTP binding molecular_function
GO:0005737: cytoplasm cellular_component
GO:0042254: ribosome biogenesis biological_process
GO:0043022: ribosome binding molecular_function
AuthorHaft DH
Entry DateApr 18 2008 8:10AM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family are a GTPase associated with ribosome biogenesis, typified by YsxC from Bacillus subutilis. The family is widely but not universally distributed among bacteria. Members commonly are called EngB based on homology to EngA, one of several other GTPases of ribosome biogenesis. Cutoffs as set find essentially all bacterial members, but also identify large numbers of eukaryotic (probably organellar) sequences. This protein is found in about 80 percent of bacterial genomes.
ReferencesRN [1] RM PMID:17981968 RT Interactions of an essential Bacillus subtilis GTPase, YsxC, with ribosomes. RA Wicker-Planquart C, Foucher AE, Louwagie M, Britton RA, Jault JM RL J Bacteriol. 2008 Jan;190(2):681-90.
Genome PropertyGenProp0802: ribosome biogenesis proteins, bacteria (HMM)