| Accession | TIGR03609 |
| Name | S_layer_CsaB |
| Function | polysaccharide pyruvyl transferase CsaB |
| Gene Symbol | csaB |
| Trusted Cutoff | 213.10 |
| Domain Trusted Cutoff | 213.10 |
| Noise Cutoff | 145.65 |
| Domain Noise Cutoff | 145.65 |
| Isology Type | equivalog |
| EC Number | 2.-.-.- |
| HMM Length | 301 |
| Mainrole Category | Cell envelope |
| Subrole Category | Surface structures |
| Gene Ontology Term | GO:0042545: cell wall modification biological_process |
| | GO:0046919: pyruvyltransferase activity molecular_function |
| Author | Haft DH |
| Entry Date | May 8 2008 2:42PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | The CsaB protein (cell surface anchoring B) of Bacillus anthracis adds a pyruvoyl group to peptidoglycan-associated polysaccharide. This addition is required for proteins with an S-layer homology domain (PF00395) to bind. Within the larger group of proteins described by Pfam model PF04230, this model represents a distinct clade that nearly exactly follows the phylogenetic distribution of the S-layer homology domain (PF00395). |
| References | RN [1]
RM PMID:10970841
RT Bacterial SLH domain proteins are non-covalently anchored to the cell surface via a conserved mechanism involving wall polysaccharide pyruvylation.
RA Mesnage S, Fontaine T, Mignot T, Delepierre M, Mock M, Fouet A
RL EMBO J. 2000 Sep 1;19(17):4473-84. |
| Genome Property | GenProp0811: S-layer homology domain-mediated cell wall binding (HMM) |
