| Accession | TIGR03621 |
| Name | F420_MSMEG_2516 |
| Function | probable F420-dependent oxidoreductase, MSMEG_2516 family |
| Trusted Cutoff | 213.15 |
| Domain Trusted Cutoff | 213.15 |
| Noise Cutoff | 163.05 |
| Domain Noise Cutoff | 163.05 |
| Isology Type | subfamily |
| HMM Length | 295 |
| Mainrole Category | Unknown function |
| Subrole Category | Enzymes of unknown specificity |
| Gene Ontology Term | GO:0008150: biological_process biological_process |
| | GO:0016491: oxidoreductase activity molecular_function |
| Author | Haft DH |
| Entry Date | Jun 13 2008 1:32PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Coenzyme F420 is produced by methanogenic archaea, a number of the Actinomycetes (including Mycobacterium tuberculosis), and rare members of other lineages. The resulting information-rich phylogenetic profile identifies candidate F420-dependent oxidoreductases within the family of luciferase-like enzymes (PF00296), where the species range for the subfamily encompasses many F420-positive genomes without straying beyond. This family is uncharacterized, and named for member MSMEG_2516 from Mycobacterium smegmatis. |
| References | RN [1]
RM PMID:20675471
RT Unexpected abundance of coenzyme F(420)-dependent enzymes in Mycobacterium tuberculosis and other actinobacteria.
RA Selengut JD, Haft DH
RL J Bacteriol. 2010 Nov;192(21):5788-98. |
| Genome Property | GenProp0002: coenzyme F420 utilization (HMM) |
