HMM Summary Page: TIGR03651

Functioncircular bacteriocin, circularin A/uberolysin family
Trusted Cutoff30.70
Domain Trusted Cutoff30.70
Noise Cutoff24.85
Domain Noise Cutoff24.85
Isology Typesubfamily
HMM Length73
Mainrole CategoryCellular processes
Subrole CategoryToxin production and resistance
AuthorHaft DH
Entry DateAug 26 2008 9:56AM
Last ModifiedFeb 14 2011 3:27PM
CommentCircular bacteriocins are antibiotic proteins made by ribosomal translation of a precursor molecular, followed by cleavage and circularization. Members of this subclass of the circular bacteriocins include circularin A from Clostridium beijerinckii, bacteriocin AS-48 from Enterococcus faecalis, uberolysin from Streptococcus uberis, and carnocyclin A from Carnobacterium maltaromaticum. The mature circularized peptides average about 70 amino acids in size.
ReferencesRN [1] RM PMID:18034824 RT Genetic features of circular bacteriocins produced by Gram-positive bacteria. RA Maqueda M, Sanchez-Hidalgo M, Fernandez M, Montalban-Lopez M, Valdivia E, Martinez-Bueno M RL FEMS Microbiol Rev. 2008 Jan;32(1):2-22. Epub 2007 Nov 20.
Genome PropertyGenProp0825: bacteriocin system, circular bacteriocin group (HMM)