HMM Summary Page: TIGR03664

AccessionTIGR03664
Namefut_nucase
Functionfutalosine hydrolase
Gene SymbolmqnB
Trusted Cutoff124.70
Domain Trusted Cutoff124.70
Noise Cutoff102.55
Domain Noise Cutoff102.55
Isology Typeequivalog
EC Number3.2.2.26
HMM Length228
AuthorSelengut J
Entry DateSep 29 2008 9:36AM
Last ModifiedFeb 14 2011 3:27PM
CommentThis enzyme catalyzes the conversion of futalosine to de-hypoxanthine futalosine in a pathway for the biosynthesis of menaquinone [1] distinct from the pathway observed in E. coli.
ReferencesRN [1] RM PMID:18801996 RT An alternative menaquinone biosynthetic pathway operating in microorganisms. RA Hiratsuka T, Furihata K, Ishikawa J, Yamashita H, Itoh N, Seto H, Dairi T RL Science. 2008 Sep 19;321(5896):1670-3. RN [2] RM PMID:19420717 RT Enzymatic properties of futalosine hydrolase, an enzyme essential to a newly identified menaquinone biosynthetic pathway. RA Hiratsuka T, Itoh N, Seto H, Dairi T RL Biosci Biotechnol Biochem. 2009 May;73(5):1137-41
Genome PropertyGenProp0829: menaquinone biosynthesis via futalosine (HMM)
GenProp0829: menaquinone biosynthesis via futalosine (HMM)