|Function||polyphosphate kinase 1|
|Domain Trusted Cutoff||465.85|
|Domain Noise Cutoff||241.75|
|Mainrole Category||Central intermediary metabolism|
|Subrole Category||Phosphorus compounds|
|Gene Ontology Term||GO:0006799: polyphosphate biosynthetic process biological_process|
| ||GO:0008976: polyphosphate kinase activity molecular_function|
| ||GO:0009358: polyphosphate kinase complex cellular_component|
|Entry Date||Jan 22 2009 1:03PM|
|Last Modified||Feb 14 2011 3:27PM|
|Comment||Members of this protein family are the enzyme polyphosphate kinase 1 (PPK1). This family is found in many prokaryotes and also in Dictyostelium. Sequences in the seed alignment were taken from prokaryotic consecutive two-gene pairs in which the other gene encodes an exopolyphosphatase. It synthesizes polyphosphate from the terminal phosphate of ATP but not GTP, in contrast to PPK2.|
RT Polyphosphate kinase from Escherichia coli. Purification and demonstration of a phosphoenzyme intermediate.
RA Ahn K, Kornberg A
RL J Biol Chem. 1990 Jul 15;265(20):11734-9.
RT Inorganic polyphosphate in the origin and survival of species.
RA Brown MR, Kornberg A
RL Proc Natl Acad Sci U S A. 2004 Nov 16;101(46):16085-7.|
|Genome Property||GenProp0840: polyphosphate kinase/exopolyphosphatase system (HMM)|
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