HMM Summary Page: TIGR03706

Gene Symbolppx
Trusted Cutoff307.00
Domain Trusted Cutoff307.00
Noise Cutoff268.00
Domain Noise Cutoff268.00
Isology Typeexception
EC Number3.6.1.11
HMM Length300
Mainrole CategoryCentral intermediary metabolism
Subrole CategoryPhosphorus compounds
Gene Ontology TermGO:0000287: magnesium ion binding molecular_function
GO:0004309: exopolyphosphatase activity molecular_function
GO:0006798: polyphosphate catabolic process biological_process
AuthorHaft DH
Entry DateJan 22 2009 1:48PM
Last ModifiedFeb 14 2011 3:27PM
CommentIt appears that a single enzyme may act as both exopolyphosphatase (Ppx) and guanosine pentaphosphate phosphohydrolase (GppA) in a number of species. Members of the seed alignment use to define this exception-level model are encoded adjacent to a polyphosphate kinase 1 gene, and the trusted cutoff is set high enough (425) that no genome has a second hit. Therefore all members may be presumed to at least share exopolyphospatase activity, and may lack GppA activity. GppA acts in the stringent response.
Genome PropertyGenProp0840: polyphosphate kinase/exopolyphosphatase system (HMM)