HMM Summary Page: TIGR03712

Functionaccessory Sec system protein Asp2
Gene Symbolasp2
Trusted Cutoff210.75
Domain Trusted Cutoff210.75
Noise Cutoff210.45
Domain Noise Cutoff210.45
Isology Typeequivalog
HMM Length511
Mainrole CategoryProtein fate
Subrole CategoryProtein and peptide secretion and trafficking
Gene Ontology TermGO:0006886: intracellular protein transport biological_process
GO:0008565: protein transporter activity molecular_function
AuthorHaft DH
Entry DateFeb 25 2009 11:57AM
Last ModifiedFeb 14 2011 3:27PM
CommentThis protein is designated Asp2 because, along with SecY2, SecA2, and other proteins it is part of the accessory secretory protein system. The system is involved in the export of serine-rich glycoproteins important for virulence in a number of Gram-positive species, including Streptococcus gordonii and Staphylococcus aureus. This protein family is assigned to transport rather than glycosylation function, but the specific molecular role is unknown.
ReferencesRN [1] RM PMID:18621893 RT Characterization of the accessory Sec system of Staphylococcus aureus. RA Siboo IR, Chaffin DO, Rubens CE, Sullam PM RL J Bacteriol. 2008 Sep;190(18):6188-96.
Genome PropertyGenProp0844: accessory Sec system for serine-rich glycoprotein transport (HMM)