| Accession | TIGR03715 |
| Name | KxYKxGKxW |
| Function | KxYKxGKxW signal peptide |
| Trusted Cutoff | 18.00 |
| Domain Trusted Cutoff | 17.60 |
| Noise Cutoff | 17.00 |
| Domain Noise Cutoff | 16.00 |
| Isology Type | domain |
| HMM Length | 23 |
| Author | Haft DH |
| Entry Date | Feb 26 2009 2:37PM |
| Last Modified | Nov 11 2011 4:33PM |
| Comment | This model describes a novel form of signal peptide that occurs as an N-terminal domain with a recognizable motif, reminiscent of the YSIRK and PEP-CTERM forms of signal peptide. This domain tends to occur on long, low-complexity (usually Serine-rich and heavily glycosylated) proteins of the Firmicutes, and (as with YSIRK) the majority of these proteins have the LPXTG cell wall-anchoring motif at the C-terminus. |
| References | RN [1]
RM PMID:17369296
RT Glycine residues in the hydrophobic core of the GspB signal sequence route export toward the accessory Sec pathway.
RA Bensing BA, Siboo IR, Sullam PM
RL J Bacteriol. 2007 May;189(10):3846-54. |
| Genome Property | GenProp0844: accessory Sec system for serine-rich glycoprotein transport (HMM-CLUST) |
| | GenProp0845: protein sorting system, KxYKxGKxW class (HMM) |
