HMM Summary Page: TIGR03725
| Accession | TIGR03725 |
| Name | T6A_YeaZ |
| Function | tRNA threonylcarbamoyl adenosine modification protein YeaZ |
| Gene Symbol | yeaZ |
| Trusted Cutoff | 69.30 |
| Domain Trusted Cutoff | 69.30 |
| Noise Cutoff | 67.75 |
| Domain Noise Cutoff | 67.75 |
| Isology Type | equivalog |
| HMM Length | 212 |
| Author | Haft DH |
| Entry Date | Mar 18 2009 4:42PM |
| Last Modified | May 7 2012 5:55PM |
| Comment | This family describes a protein family, YeaZ, now associated with the threonylcarbamoyl adenosine (t6A) tRNA modification. Members of this family may occur as fusions with ygjD (previously gcp) or the ribosomal protein N-acetyltransferase rimI, and is frequently encoded next to rimI. |
| References | RN [1] RM PMID:22378793 RT Biosynthesis of Threonylcarbamoyl Adenosine (t6A), a Universal tRNA Nucleoside. RA Deutsch C, El Yacoubi B, de Crecy-Lagard V, Iwata-Reuyl D RL J Biol Chem. 2012 Apr 20;287(17):13666-73. RN [2] RM PMID:16617437 RT Structural characterization of Salmonella typhimurium YeaZ, an M22 O-sialoglycoprotein endopeptidase homolog. RA Nichols CE, Johnson C, Lockyer M, Charles IG, Lamb HK, Hawkins AR, Stammers DK RL Proteins. 2006 Jul 1;64(1):111-23. |
| Genome Property | GenProp1060: tRNA N6-threonylcarbamoyladenosine modification (HMM) |